ABSTRACT
Objective:To evaluate the relationship between preoperative widespread pain and chronic post-surgical pain (CPSP) following total knee arthroplasty (TKA) in the patients with knee osteoarthritis.Methods:Two hundred American Society of Anesthesiologists physical status Ⅰ-Ⅲ patients with knee osteoarthritis, aged 40-70 yr, undergoing elective the first unilateral primary TKA under general anesthesia, were enrolled.The widespread pain index, visual analogue scale score, Hospital Anxiety and Depression Scale and Central Sensitization Inventory scores were recorded at 1 day before surgery.The patients were divided into CPSP-positive group and CPSP-negative group according to visual analogue scale score at 6 months after surgery.Risk factors for CPSP were analyzed by logistic regression.Results:The results of logistic regression analysis showed that increased preoperative widespread pain index score, Central Sensitization Inventory score and Hospital Anxiety and Depression Scale score and female were risk factors for CPSP after TKA.Conclusions:Preoperative widespread pain is a risk factor for CPSP following TKA in the patients with knee osteoarthritis.
ABSTRACT
Objective To observe anesthetic effects of ultrasound-guided rectus sheath block (RSB)in peritoneal dialysis catheter implantation in patients with end-stage renal disease. Methods A total of 75 uremic patients (38 males,37 females,aged 18-65 years,BMI 18.5-24 kg/m2,ASA physical status Ⅲ),scheduled for elective peritoneal dialysis catheterization,were randomly divided into three groups (n=25 each)using a random number table:group A:total intra-venous anesthesia;group B:rectus sheath block,0.5% ropivacaine 15 ml were injected into the lat-eral rectus sheath;group C:local infiltration anesthesia was performed with 1% lidocaine and 0.5% ropivacaine.The mean arterial pressure and heart rate at the point of entering the operating room (T0),10 min after anesthesia induction (T1),at the beginning of operation (T2),20 min after the beginning of operation(T3),and at the end of the operation(T4)were recorded.The VAS score and Ramsay score at 2,4,8,12,24 h after surgery were recorded.The duration of operation and the oc-currence of adverse reactions were recorded.Results In group A,compared with T0,MAP and HR at T1-T3decreased significantly (P<0.05).In group B,there were no difference among T0-T4.In group C,compared with T0,T1and T4,MAP and HR at T2,T3increased significantly(P<0.05). Compared with group C,the duration of operation time in group A and group B decreased significantly (P<0.05).Compared with group A and group C,the VAS score at each point of group B was lower (P<0.05).Compared with group B,the total number of remediation analgesia in group C increased significantly(P<0.05).There was no adverse reaction in all three groups.Conclusion Ultra-sound-guided rectus sheath block anesthesia is safe and effective in peritoneal dialysis catheter implanta-tion patients with end-stage renal disease,and is worthy of clinical promotion.
ABSTRACT
Objective To investigate the biological characteristics , therapy selection of tubular breast carcinoma.Relationship between axillary lymph node metastasis and other factors are analyzed retrospectively . Methods Tubular carcinoma patients were collected in our hospital from June ,1987 to March,2014.Paraffin tis-sues were re-checked again by pathology doctors and all patients were performed follow -up by telephone to e-valuate the prognosis .Results Sixty eight cases of tubular carcinoma of the breast were chosen .Axillary lymph node metastasis was closely related to tumor size and tumor grade in our research .In all patients ,only one patient was relapsed ,24 patients died of other diseases ,without distant metastasis or death of breast cancer .Conclusion Tubular breast carcinoma has a good prognosis with low recurrence rate .The treatment of tubular carcinoma is not quite reasonable .Preoperative core needle biopsy and surgery axillary staging should be paid more attention and breast conserving rate is still needed for improvement .